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I've often wondered if it's not possible to drag some sort of burden with you from one life to the next (because I've noticed some disturbing parallels myself), but I'm still unsure about how karma plays in. I don't think either karma or astrology has all that big of a control over life, certainly not as much as choice.
I view Karma as something literal and observable in one's own life time. The many choices I made as a kid determined who I became today. This in turn has had an effect on those around me. What determined what choices I made as a kid depended on what choices my parents made before I was born.